P-ADC™
PRECISION-driven
AIMEDBIO's PLATFORM
for DEFINITE CURE
AIMEDBIO's PLATFORM
for DEFINITE CURE
Full-Cycle Engine for ADC Development:
From Unmet Medical Needs to Clinical Success
From Unmet Medical Needs to Clinical Success
P-ADC™ is our internal, end-to-end development platform,
engineered to seamlessly connect unmet medical needs with clinical success.
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01Target Discovery & Selection
- Discovery of clinically meaningful targets based on unmet medical needs.
- Target assessment based on expression profiles in tumor versus normal tissues.
- Validation of efficacy and clinical suitability using patient-derived data.
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02Antibody Discovery & Engineering
- Proprietary antibody screening platform utilizing patient-derived cells
- Antibody characterization focused on internalization and tumor selectivity
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03ADC Optimization
- Early efficacy and clinical fitness validation using PDC/PDX models.
- Optimization of linker-payload combinations guided by target and indication biology
- Data-driven strategies to enhance the overall clinical suitability of the ADC
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04Translational Research Reflecting Clinical Strategy
- Establishing a clear clinical positioning through early development strategy
- Early acquisition of critical data required to support clinical positioning
- Selective and precise translational studies to maximize clinical relevance
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05Final Candidate Selection
- Selection of candidates with clear First-in-Class or Best-in-Class potential
- Selection of candidates aligned with a robust and well-defined clinical development strategy
- Target Discovery & Selection
- Antibody Discovery & Engineering
- ADC Optimization
- Translational Research Reflecting Clinical Strategy
- Final Candidate Selection
