Publications

Selected Publication

A strong track record of publication in the area of brain disease and big data

BLOOD-BRAIN BARRIER RESEARCH

Simplified in vitro 3D co-culture-based blood-brain barrier model using transwell

Biochem Biophys Res Commun. September 2022

BLOOD-BRAIN BARRIER RESEARCH

Functional validation of the simplified in vitro 3D Co-culture based BBB model

Biochem Biophys Res Commun. October 2022

NOVEL THERAPEUTICS SCREENING

High-Content Analysis-Based Sensitivity Prediction and Novel Therapeutics Screening for c-Met-Addicted Glioblastoma

Cancers (Basel) January 2021

BRAIN IMMUNE MODULATION

Transcriptional regulatory networks of tumor-associated macrophages that drive malignancy in mesenchymal glioblastoma

Genome Biology August 2020

PHARMACOGENOMIC LANDSCAPE

Comprehensive pharmacogenomic characterization of gastric cancer

Genome Medicine December 2020

PHARMACO-PROTEOMIC LANDSCAPE

integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities

Genome Medicine December 2020

(Publication at the SMC IRCR)

TUMOR PROGRESSION MECHANISM

PIP4K2A as a negative regulator of PI3K in pTEN-deficient glioblastoma

Journal of Experimental Medicine May 2019

TUMOR EVOLUTION & CHROMOSOMAL ELEMENTS

Longitudinal molecular trajectories of diffuse glioma in adults

Nature November 2019

PHARMACOGENOMIC LANDSCAPE

Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers

Genome Biology November 2019

(Publication at the SMC IRCR)

TUMOR EVOLUTION & CHROMOSOMAL ELEMENTS

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

Nature Genetics April 2018

TUMOR PROGRESSION MECHANISM

Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors

Cancer Cell July 2018

TUMOR MESENCHYMAL TRANSITION

A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma

Nature Cell Biology September 2018

PHARMACOGENOMIC LANDSCAPE

Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy

Nature Genetics September 2018

MUTATIONAL LANDSCAPE IN BRAIN TUMOR

Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor

Cell November 2018

(Publication at the SMC IRCR)

TUMOR EVOLUTION

Spatiotemporal Evolution of the Primary Glioblastoma Genome

Cancer Cell September 2015

TUMOR EVOLUTION MODEL

Clonal evolution of glioblastoma under therapy

Nature Genetics July 2016

TUMOR HETEROGENEITY & DRUG SELECTION

Spatiotemporal genomic architecture informs precision oncology in glioblastoma

Nature Genetics March 2017

TUMOR EVOLUTION & IMMUNE SIGNATURES

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

Cancer Cell July 2017

Our Science

Publications

Publications

BLOOD-BRAIN BARRIER RESEARCH

BLOOD-BRAIN BARRIER RESEARCH

NOVEL THERAPEUTICS SCREENING

BRAIN IMMUNE MODULATION

PHARMACOGENOMIC LANDSCAPE

PHARMACO-PROTEOMIC LANDSCAPE

TUMOR PROGRESSION MECHANISM

TUMOR EVOLUTION & CHROMOSOMAL ELEMENTS

PHARMACOGENOMIC LANDSCAPE

TUMOR EVOLUTION & CHROMOSOMAL ELEMENTS

TUMOR PROGRESSION MECHANISM

TUMOR MESENCHYMAL TRANSITION

PHARMACOGENOMIC LANDSCAPE

MUTATIONAL LANDSCAPE IN BRAIN TUMOR

TUMOR EVOLUTION

TUMOR EVOLUTION MODEL

TUMOR HETEROGENEITY & DRUG SELECTION

TUMOR EVOLUTION & IMMUNE SIGNATURES